Types of CMT

CMT 1

CMT 1 is caused by defective genes that are involved in the production of the myelin sheath. The defects cause the myelin sheath to slowly break down. CMT 1 is the most common type of CMT, accounting for around 35% of cases.

CMT 2

CMT 2 is caused be defects in the axon. It is less common than CMT 1, accounting for around 17% of cases.

CMT 3

CMT 3, also known as Dejerine-Sottas disease, is a rare and severe type of CMT that affects the myelin sheath. It is characterised by extreme muscle weakness and sensory problems. Unlike many other types of CMT, the symptoms normally begin in early childhood.

CMT 4

CMT 4 is another rare type of CMT that also affects the myelin sheath. The exact genes that cause CMT 4 have not yet been identified, but it is thought that several different genetic processes may be involved. As with CMT 3, the symptoms of CMT 4 usually begin in childhood, and many people with the condition are unable to walk.

CMT X

CMT X is a type of CMT that is caused by a mutation in the 'x' chromosome, which is one of the chromosomes that determine what sex you are. CMT X is more common in men than women, and it is estimated to account for around 10% of CMT cases.